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The Tottenham defender scored on two occasions as Spurs prolonged their unbeaten run in away games in the top division and handed Everton their initial loss at Hill Dickinson Stadium.

Everton were undefeated in their five previous fixtures at their new ground at the dockside location, having departed Goodison Park behind after 133 years at the conclusion of last season.

But Tottenham's leader the Dutchman pounced on two occasions from set-pieces in the first half to put their strong form at jeopardy, and they were unable to mount a comeback before Pape Matar Sarr - assisted by ex-Everton forward Richarlison - headed home a third to seal the victory.

Jake O'Brien believed he had equalized the scores a short while after Van de Ven's first goal, glancing a bullet header past the Spurs keeper from an Everton corner.

The Portuguese striker, meanwhile, missed a handful of opportunities, while Vicario made a series of fine saves to ensure the London club went five away games unbeaten in the Premier League.

But the video assistant referee intervened, advising Craig Pawson to review the goal on the screen and the referee decided that the winger and the attacker were in offside positions and had interfered with the Tottenham goalkeeper.

This victory elevates the manager's side up to third in the division, a handful of points off north London rivals and table-toppers the Gunners.

Everton stay 14th and sit six points clear of the drop zone.

Spurs breakdown: The defender fulfils role at each end of the field

After a uninspiring weekday performance in the European competition against Monaco, where they mustered a only two shots on target, the manager opted for the French striker up front instead of former Toffees player the Brazilian.

The summer signing was unable to make much of an impact before being substituted for Richarlison after 60 minutes on the pitch, but it turns out he wasn't needed in the end.

Centre-back Van de Ven transformed into an attacking force to be reckoned with.

Spurs' first goal came from a well-worked set-piece play, with the midfielder heading the ball back across the face of goal for an free Van de Ven to score.

And the captain - stepping up as captain in the Argentine's unavailability - added his next goal in first-half stoppage time as he rose above Jordan Pickford to head home.

Van de Ven was equally outstanding in defensive duties, combining well with Kevin Danso as the duo handled excellently with the numerous deliveries thrown their way by the opposition.

Everton analysis: Everton missing finishing touch

The club's recent stadium had been a fortress, but it seems the novelty may have worn off slightly and supporters flocked to the gates after the midfielder's third for Spurs.

The end in Everton's winning streak at home won't be a major concern for the manager, but their attacking woes will be.

The forward and Thierno Barry - the Toffees' pair of established strikers - had netted only a single goal combined before the weekend's match.

And they were unable to contribute to that miserable record on a damp and dreary evening on Merseyside.

Beto's performance was epitomized when he chose to bicycle-kick a golden opportunity from close range, despite having space and time to readjust for a simpler shot that would have tested the keeper.

Barry, too, failed to make an impact after replacing the starter in the 65th minute.

It wasn't for a lack of opportunity. The majority of Everton's attacks came through Grealish and Ndiaye, who relentlessly delivered threatening crosses into the Tottenham penalty area.

Upcoming fixtures for both teams?

The Toffees: Moyes' men travel to Sunderland in the top flight on Monday, 3 November at 20:00 GMT.

Spurs: Spurs travel to Newcastle's ground on Wednesday, 29 October for their fourth-round Carabao Cup match against the Magpies.